An alien virus is spreading uncontrollable superpowers through the city of Chicago. Handling intense situations is just part of the job for police officer Dick Urbanski. But now that his city's been quarantined, he faces a crisis unlike any ever seen on Earth. Despite the help of Dr. Ai Tanaka, Dick is unable to keep millions of panicked, superpowered citizens under control. Can he stay alive long enough to find a cure--or will the government be forced to blow Chicago off the map?